2006
Lee, Y.A., B.H. Yun, S.K. Kim, Y. Margolin, P.C. Dedon, N.E. Geacintov and V. Shafirovich (2006) Mechanisms of guanine oxidation in DNA by carbonate radical anion, a decomposition product of nitrosoperoxycarbonate. Eur. J. Chem., in press.
Lee, Y.A., B.H. Yun, S.K. Kim, Y. Margolin, P.C. Dedon, N.E. Geacintov and V. Shafirovich (2006) Base sequence effects on guanine oxidation by carbonate radical anions: Kinetics and gel electrophoresis studies. J. Am. Chem. Soc., in press.
Pang, B., X. Zhou, H. Yu, M. Dong, K. Taghizadeh, J.S. Wishnok, S.R. Tannenbaum and P.C. Dedon (2007) Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation. Carcinogenesis, in press.
Jiang, T., X. Zhou, K. Taghizadeh, M. Dong and P.C. Dedon (2006) N-Formylation of lysines in histone proteins: A novel secondary modification arising from oxidative DNA damage. Proc. Natl. Acad. Sci. USA, 104: 60-65.
Fry, R.C., M. DeMott, J.P. Cosgrove, T.J. Begley, L.D. Samson and P.C. Dedon (2006) The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA. BMC Genomics 7(1): 313.
Dedon, P.C. and M.C. Barth (2006) Oxidatively damaged DNA and inflammation, in Oxidative Damage to Nucleic Acids, ed. M. Evans and M. Cooke, Landes Bioscience/Eurekah.com, Austin, TX.
Margolin, Y., and P.C. Dedon (2006) A general method for quantifying sequence effects on nucleobase oxidation in DNA, in Methods in Molecular Biology, ed. R. Uppu, Humana Press, Totowa, NJ, in press.
Reiter, T.A., B. Pang, P.C. Dedon, and B. Demple (2006) Resistance to nitric oxide-induced necrosis in heme oxygenase-1 over-expressing pulmonary epithelial cells associated with decreased lipid peroxidation. J. Biol. Chem., 281: 36603-36612.
Chen, B., C.C. Vou, M.C. Byrns, P.C. Dedon, and L.A. Peterson (2006) Formation of 1,4-dioxo-2-butene-derived adducts of 2'-deoxyadenosine and 2'-deoxycytosine in oxidized DNA. Chem. Res. Toxicol., 19: 982-985.
Margolin, Y., J.-F. Cloutier, V. Shafirovich, N. Geacintov and P.C. Dedon (2006) Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nature Chem. Biol., 2: 365-366.
Zipes, D.P., M.A. Pfeffer, N.J. Zvaifler, R.J. Glassock, S. Gilman, A. Muñoz, V. Gogolak, L. Gordis, P.C. Dedon, F.P. Guengerich, S.I. Wasserman, J.L. Witztum, and G.N. Wogan (2006) Rosuvastatin: An independent analysis of risks and benefits. MedGenMed, 8: 73; available at: http://medgenmed.medscape.com/viewarticle/533930.
Li, C.-Q., B. Pang, T. Kiziltepe, L.J. Trudel, B.P. Engelward,P.C. Dedon, and G.N. Wogan (2006) Threshold cytotoxicity and genotoxicity induced by nitric oxide in human lymphoblastoid cells expressing wild-type or null p53. Chem. Res. Toxicol., 19: 399-406.
Dong, M. and P.C. Dedon (2006) Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide. Chem. Res. Toxicol. 19: 50-57.
Dedon, P., M. Barth, B. Chen, M. DeMott, V. Dendroulakis, M. Dong, S. Kalinga, E. Elmquist, Y. Margolin, B. Pang, X. Zhou (2006) Diverse mechanisms of endogenous nucleobase deamination in DNA and RNA, in Advances in Molecular Toxicology, ed. J. Fishbein, Wiley, NY.
Dong, M., V. Vongchampa, L. Gingipalli, J.-F. Cloutier, Y.W. Kow, T. O'Connor and P.C. Dedon (2006) Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mut. Res. 594: 120-134.
2005
Zhou, X., K. Taghizadeh and P. Dedon (2005) Chemical and biological evidence for base propenals as the major source of the endogenous M 1dG adduct in cellular DNA. J. Biol. Chem. 280 : 25377-25382.
Zhou, X., R. Liberman, P. Skipper, Y. Margolin, S. Tannenbaum, P. Dedon (2005) Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: Application to g -radiation and peroxynitrite. Anal. Biochem. 343 : 84-92.
Li, C.-Q., T.L. Wright, M. Dong, Y.E.M. Dommels, P.C. Dedon, S.R. Tannenbaum, and G.N. Wogan (2005) Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models. Free Rad. Biol. Med. 39 : 1489-1498.
Kiziltepe, T., A. Yan, M. Dong, V.S. Jonnalagadda, P.C. Dedon, and B.P. Engelward (2005) Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells. Chem. Biol. 12 : 357-369.
Kim, M.Y., M. Dong, P.C. Dedon and G.N. Wogan (2005) Effects of peroxynitrite dose and dose-rate on DNA damage and mutation in the supF shuttle vector. Chem. Res. Toxicol., 18: 76-86.
Collins, C., X. Zhou, R. Wang, M. Barth, T. Jiang, J. Coderre and P. Dedon (2005) Differential oxidation of deoxyribose in DNA by g - and a -radiation. Rad. Res., 163: 654-662.
Chen, B., T. Bohnert, X. Zhou and P.C. Dedon (2004) 5'-(2-Phosphoryl-1,4-dioxobutane) as a product of 5'-oxidation of deoxyribose in DNA: Elimination as trans-1,4-dioxo-2-butene and approaches to analysis. Chem. Res. Toxicol., 17 :1406-1413.
Bohnert, T., L. Gingipalli, P.C. Dedon (2004) Reaction of 2'-deoxyribonucleosides with cis- and trans-1,4-dioxo-2-butene. Biochem. Biophys. Res. Commun., 323: 838-844.
Dedon, P.C. and S.R. Tannenbaum (2004) Reactive nitrogen species in the chemical biology of inflammation. Arch. Bioch. Biophys., 423 : 12-22.
