186) Li W, Chan CK, Liu Y, Yao J, Mitic B, Kostić EN, Milosavljević B, Davinić I, Orem WH, Tatu CA, Dedon PC, Pavlović NM, Chan W (2018) Aristolochic Acids as Persistent Soil Pollutants: Determination of Risk for Human Exposure and Nephropathy from Plant Uptake. J Agric Food Chem, 66: 11468-11476. PMID: 30286603 DOI: 10.1021/acs.jafc.8b04770.

185) Ng CS, Sinha A, Aniweh Y, Nah Q, Babu IR, Gu C, Chionh YH, Dedon PC, Preiser PR (2018) tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum. Mol Sys Biol, 14: e8009. PMCID: PMC6171970 DOI: 10.15252/msb.20178009.

184) Wang L, Jiang S, Deng Z, Dedon P, Chen S (2018) DNA phosphorothioate modification — a new multi-functional epigenetic system in bacteria. FEMS Micro Rev, 2018 Oct 4. doi: 10.1093/femsre/fuy036. PMID: 30289455.

183) Bi X, Yin J, Rao R, Banerjeem B, Balamkundu S, Zhang D, Zhang D, Dedon P, Liu C-F (2018) Aldehyde–aminoethanethioamide condensation as a catalyst-free bioorthogonal reaction for protein and live cell labeling. Org Lett. 2018 Dec 5. doi: 10.1021/acs.orglett.8b03195. [Epub ahead of print]; PMID: 30517009.

182) Li Y, Zhong W, Koay AZ, Ng HQ, Ngo A, Koh-Stenta X, Nah Q, Lim SH, Larsson A, Keller TH, Lescar J, Hill J, Dedon PC, Kang C (2018) Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase. Biomol NMR Assign, Oct 8. doi: 10.1007/s12104-018-9849-9. PMID: 30298375.

181) Yuan Y, Hutinet G, Gamboa Valera J, Hu J, Hillebrand R, Gustafson A, Iwata-Reuyl D, Dedon PC, and de Crécy-Lagard V (2018) Identification of the minimal bacterial 2'-deoxy-7-amido-7-deazaguanine synthesis machinery. Mol Micro, 110: 469-483. PMCID: PMC6207457, DOI: 10.1111/mmi.14113.

180) Jaroensuk J, Wong YH, Zhong W, Liew C, Maenpuen S, Atichartpongkul S, Chionh YH, Nah JQH, Thongdee N, McBee M, Prestwich E, DeMott M, Chaiyen P, Mongkolsuk S, Dedon P, Lescar J, Fuangthong M (2018) Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa. Submitted.

179) Zhong W, Koay AZ, Ngo A, Nah Q, Wong YH, Chionh YH, Li Y, Ng HQ, Stenta CK, Poulsen A, Kang C, Keller TH, Lescar J, Hill J, Dedon PC (2018) Discovery and identification of bacterial tRNA-(N1G37) methyltransferase (TrmD) inhibitors with antibacterial activity by high-throughput screening. Submitted.

178) Rothenberg DA, Taliaferro JM, Huber SM, Begley TJ, Dedon PC, Burge CB, White FM (2018) A proteomics approach to profiling the temporal translational response to stress and growth. iScience. 9: 367-381. DOI: 10.1016/j.isci.2018.11.004. PMCID: PMC6249402.

177) Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, Fortune S, Dedon PC, Pellegrini M, Modlin RL (2018) Mycobacterium tuberculosis transfer RNA induces IL-12p70 via synergistic activation of pattern recognition receptors within a cell network. J Immunol, 200: 3244-3258. PMCID: PMC5916334.

176) Chan C, Pham P, Dedon PC, Begley TJ (2018) Lifestyle modifications: Coordinating the tRNA epitranscriptome and an alternative genetic code to adapt translation during stress responses. Genome Biol, 19: 228. https://doi.org/10.1186/s13059-018-1611-1.

175) Gu C, Ramos J, Begley U, Dedon PC, Fu D, Begley TJ (2018) Phosphorylation of human TRM9L is a critical regulator of oxidative stress survival and tumor growth suppression. Sci Adv, 4: eaas9184. PMCID: PMC6040840.

174) Zhong W, Cui L, Goh BC, Cai Q, Ho P, Chionh YH, Yuan M, El Sahili A, Fothergill-Gilmore LA, Walkinshaw MD, Lescar J, Dedon PC (2017) Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8: 1986. PMCID: PMC5719368.

173) Edrissi B, Taghizadeh K, Moeller B, Yu R, Kracko D, Doyle-Eisele M, Swenberg J, Dedon PC (2017) N6-Formyllysine as a biomarker of formaldehyde exposure: Formation and loss of N6-formyllysine in nasal epithelium in long-term, low-dose inhalation studies in rats. Chem Res Toxicol, 30: 1572-1576. PMCID: PMC5807069.

172) Bacusmo JM, Orsini SS, Hu J, DeMott M, Thiaville PM, Elfarash A, Paulines MJ, Rojas-Benítez D, Meineke B, Deutsch C, Iwata-Reuyl D, Limbach PA, Dedon PC, Rice KC, Shuman S, de Crécy-Lagard V (2017) The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans. RNA Biol, 15: 508-517. PMCID: PMC6103680.

171) Braun DA, Rao J, Mollet G, Schapiro D, Daugeron M-C, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, Schmidt JM, Lawson JA, Schanze D, Ashraf S, Ullmann JFP, Hoogstraten CA, Boddaert N, Collinet B, Martin G, Liger D, Lovric S, Furlano M, Guerrera IC, Sanchez-Ferras O, Hu J, Boschat A-C, Sanquer S, Menten B, Vergult S, De Rocker N, Airik M, Hermle T, Shril S, Widmeier E, Gee HY, Choi WI, Sadowski CE, Pabst WL, Warejko J, Daga A, Basta-Leberre T, Matejas V, Scharmann K, Kienast SD, Behnam B, Beeson B, Begtrup A, Bruce M, Ch'ng G-S, Lin S-P, Chang J-H, Chen C-H, Cho MT, Gaffney PM, Gipson PE, Hsu C-H, Kari JA, Ke Y-Y, Kiraly-Borri C, Lai W-M, Lemyre E, Littlejohn RO, Masri A, Moghtaderi M, Nakamura K, Ozaltin F, Praet M, Prasad C, Prytula A, Roeder E, Rump P, Schnur RE, Shiihara T, Sinha M, Soliman NA, Soulami K, Sweetser DA, Tsai W-H, Tsai J-D, Topaloglu R, Vester U, Viskochil DH, Vatanavicharn N, Waxler JL, Wierenga KJ, Wolf MTF, Wong S-N, Leidel SA, Truglio G, Dedon PC, Poduri A, Mane S, Lifton RP, Bouchard M, Kannu P, Chitayat D, Magen D, Calleweart B, van Tilbeurgh H, Zenker M, Antignac C, Hildebrandt F (2017) Mutations in the KEOPS complex genes cause nephrotic syndrome with primary microcephaly. Nat Genetics, 49(10):1529-1538. PMCID: PMC5819591.

170) Wong YH, Goh BC, Lim SY, Teo EW, Lim A, Dedon PC, Hanson B, MacAry P, Lescar J (2017) Structural mimicry of the dengue virus envelope glycoprotein revealed by the crystallographic study of an idiotype-anti-idiotype Fab complex. J Virol, 91(17): e00406-17. PMCID: PMC5553163.

169) Kan L, Grozhik AV, Vedanayagam J, Patil DP, Pang N, Lim, Huang YC, Joseph B, Lin CJ, Guo J, Yan D, Kondo S, Deng WM, Dedon PC, Jaffrey SR, Lai EC (2017) The m6A pathway facilitates sex determination in Drosophila. Nat Commun, 8:15737. PMCID: PMC5500889.

168) McBee ME, Chionh YH, Sharaf ML, Ho P, Cai WLM, Dedon PC (2017) Production of superoxide in bacteria is stress- and cell state-dependent: A gating-optimized flow cytometry method that minimizes ROS measurement artifacts with fluorescent dyes. Frontiers Micro, 8: 459. PMCID: PMC5359317.

167) Chen C, Wang L. Chen S, Wu X, Gu M, Chen X, Deng Z, Dedon PC, Chen S (2017) Convergence of DNA methylation and phosphorothioation epigenetics in bacterial genomes. Proc Natl Acad Sci, 114: 4501-4506. PMCID: PMC5410841.

166) Edvardson S, Prunetti L, Arraf A, Haas D, Bacusmo JM, Hu JF, Ta-Shma A, Dedon PC, de Crécy-Lagard V, Elpeleg O. (2017) tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy. Eur J Hum Genet. 25: 545-551. PMCID: PMC5437908.

165) Kellner S, DeMott, MS, Cheng CP, Russell B, Cao B, Dedon PC (2017) Oxidation of labile phosphorothioate DNA modifications leads to lethal genomic instability. Nat Chem Biol, 13: 888-894. PMCID: PMC5577368.

164) Chionh YH, Babu IR, Hia F, Lin W, Dziergowska A, Malkiewicz A, Begley TJ, Alonso S, Dedon PC (2016) tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence. Nat Commun, 7: 13302. PMCID: PMC5114619.

163) Jaroensuk J, Atichartpongkul S, Chionh YH, Wong YH, Liew C, McBee M, Thongdee N, Prestwich E, DeMott M, Mongkolsuk S, Dedon P, Lescar J, Fuangthong M (2016) Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa. Nucleic Acids Res, 44(22):10834-10848. PMCID: PMC5159551.

162) Xu L, Liu X, Sheng N, Oo KS, Liang J, Chionh YH, Xu J, Ye F, Gao Y-G, Dedon P, Fu X-Y (2017) Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans. J Biol Chem, 292(35): 14695-14703. PMCID: PMC5582859.

161) Shen L, Liang Z, Gu X, Chen Y, Teo ZWN, Hou X, Cai WM, Dedon PC, Liu L, Yu H (2016) N6-methyladenosine RNA modification regulates shoot stem cell fate in Arabidopsis. Dev Cell 38: 186-200. PMCID: in process.

160) Doyle F, Leonardi A, Endres L, Tenenbaum SA, Dedon PC, Begley TJ (2016) Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT codon utilization tool. Methods 107: 98-109.

159) Wang J, Dong H, Chionh YH, McBee ME, Sasilada S, Cunningham RP, Shi PY, Dedon PC (2016) The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA. Nucleic Acids Res 44(18): 8962-8975. PMCID: PMC5062971.

158) Molinie B, Wang J, Lu Z-X, Lim KS, Van Wittenberghe N, Howard BD, Daneshvar K, Hillebrand R, Dedon P, Mullen A, Xing Y, Giallourakis CG (2016) m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveals the census and complexity of the m6A epitranscriptome. Nat Methods 13: 692-698. PMCID: in process.

157) Thiaville JJ, Kellner SM, Yuan Y, Hutineta G, Thiaville PC, Jumpathong W, Mohapatra S, Brochier-Armanet C, Letarov AV, Hillebrand R, Malik CK, Rizzo C, Dedon PC, de Crécy-Lagard V (2016) Novel genomic island modifies DNA with 7-deazaguanine derivatives. Proc Natl Acad Sci USA 113: E1452–E1459. PMCID: PMC4801273.