Published papers    |   Conference Posters    |  

Past two years; full list at https://www.ncbi.nlm.nih.gov/myncbi/peter.dedon.1/bibliography/public/

Quaiyum S, Yuan Y, Sun G, N Ratnayake RMM, Hutinet G, Dedon PC, Minnick MF, de Crécy-Lagard V. (2023) Queuosine Salvage in Bartonella henselae Houston 1: A Unique Evolutionary Path. bioRxiv. 2023 Dec 6;. doi: 10.1101/2023.12.05.570228. PMCID: PMC10723273.

Del Dedo JE, Segundo RL, Vázquez-Bolado A, Sun J, García-Blanco N, Suárez MB, García P, Tricquet P, Chen JS, Dedon PC, Gould KL, Hidalgo E, Hermand D, Moreno S. (2023) The Greatwall-Endosulfine-PP2A/B55 pathway controls entry into quiescence by promoting translation of Elongator-tuneable transcripts. Res Sq. 2023 Dec 5;. doi: 10.21203/rs.3.rs-3616701/v1. PMCID: PMC10723533.

Mitchener MM, Begley TJ, Dedon PC. (2023) Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins. Acc Chem Res. 2023 Dec 5;56(23):3504-3514. doi: 10.1021/acs.accounts.3c00572. Epub 2023 Nov 22. PMCID: PMC10702489.

Guilbaud A, Ghanegolmohammadi F, Wang Y, Leng J, Kreymerman A, Gamboa Varela J, Garbern J, Elwell H, Cao F, Ricci-Blair EM, Liang C, Balamkundu S, Vidoudez C, DeMott MS, Bedi K, Margulies KB, Bennett DA, Palmer AA, Barkley-Levenson A, Lee RT, Dedon PC. (2023) Discovery adductomics provides a comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans. Nucleic Acids Res. 2023 Nov 10;51(20):10829-10845. doi: 10.1093/nar/gkad822. PMCID: PMC10639045.

Chan C, Kwan Sze NS, Suzuki Y, Ohira T, Suzuki T, Begley TJ, Dedon PC. (2023) Dengue virus exploits the host tRNA epitranscriptome to promote viral replication. bioRxiv. 2023 Nov 6;. doi: 10.1101/2023.11.05.565734. PMCID: PMC10659268.

Burdick JT, Comai A, Bruzel A, Sun G, Dedon PC, Cheung VG. (2023) Nanopore-based direct sequencing of RNA transcripts with 10 different modified nucleotides reveals gaps in existing technology. G3 (Bethesda). 2023 Nov 1;13(11). doi: 10.1093/g3journal/jkad200. PMCID: PMC10627276.

Rosa C, Singh P, Chen P, Sinha A, Claës A, Preiser PR, Dedon PC, Baumgarten S, Scherf A, Bryant JM. (2023) Cohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite. EMBO Rep. 2023 Oct 9;24(10):e57090. doi: 10.15252/embr.202357090. Epub 2023 Aug 18. PMCID: PMC10561359.

Cui L, Balamkundu S, Liu CF, Ye H, Hourihan J, Rausch A, Hauß C, Nilsson E, Hoetzinger M, Holmfeldt K, Zhang W, Martinez-Alvarez L, Peng X, Tremblay D, Moinau S, Solonenko N, Sullivan MB, Lee YJ, Mulholland A, Weigele PR, de Crécy-Lagard V, Dedon PC, Hutinet G. (2023) Four additional natural 7-deazaguanine derivatives in phages and how to make them. Nucleic Acids Res. 2023 Sep 22;51(17):9214-9226. doi: 10.1093/nar/gkad657. PMCID: PMC10516641.

Olsen NS, Nielsen TK, Cui L, Dedon P, Neve H, Hansen LH, Kot W. (2023) A novel Queuovirinae lineage of Pseudomonas aeruginosa phages encode dPreQ0 DNA modifications with a single GA motif that provide restriction and CRISPR Cas9 protection in vitro. Nucleic Acids Res. 2023 Sep 8;51(16):8663-8676. doi: 10.1093/nar/gkad622. PMCID: PMC10484667.

Lee WL, Sinha A, Lam LN, Loo HL, Liang J, Ho P, Cui L, Chan CSC, Begley T, Kline KA, Dedon P. (2023) An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis. Nat Commun. 2023 Jul 11;14(1):4093. doi: 10.1038/s41467-023-39790-x. PMCID: PMC10336011.

Goh BC, Larsson S, Dam LC, Ling YHS, Chua WLP, Abirami R, Singh S, Ong JLE, Teo JWP, Ho P, Ingham PW, Pethe K, Dedon PC. (2023) Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish. JAC Antimicrob Resist. 2023 Jun;5(3):dlad052. doi: 10.1093/jacamr/dlad052. eCollection 2023 Jun. PMCID: PMC10164658.

Jiang L, Roberts R, Wong M, Zhang L, Webber CJ, Kilci A, Jenkins M, Sun J, Sun G, Rashad S, Dedon PC, Daley SA, Xia W, Ortiz AR, Dorrian L, Saito T, Saido TC, Wolozin B. (2023) Accumulation of m(6)A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP(NL-G-F) /MAPT(P301S) mouse model of Alzheimer's disease. Res Sq. 2023 May 18;. doi: 10.21203/rs.3.rs-2745852/v1. PMCID: PMC10246280.

Gedara SH, Wood E, Gustafson A, Liang C, Hung SH, Savage J, Phan P, Luthra A, de Crécy-Lagard V, Dedon P, Swairjo MA, Iwata-Reuyl D. (2023) 7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system. Nucleic Acids Res. 2023 May 8;51(8):3836-3854. doi: 10.1093/nar/gkad141. MCID: PMC10164549.

Wilbanks B, Pearson K, Byrne SR, Bickart LB, Dedon PC, Maher LJ 3rd. (2023) DNA Modifications Enabling Proximity Biotinylation. Bioconjug Chem. 2023 Mar 8;34(4):611-5. doi: 10.1021/acs.bioconjchem.2c00475. [Epub ahead of print] PMCID: PMC10119920.

Dedon PC, Begley TJ. (2022) Dysfunctional tRNA reprogramming and codon-biased translation in cancer. Trends Mol Med. 2022 Nov;28(11):964-978. doi: 10.1016/j.molmed.2022.09.007. Epub 2022 Oct 11. Review. PMCID: PMC10071289.

Huber SM, Begley U, Sarkar A, Gasperi W, Davis ET, Surampudi V, Lee M, Melendez JA, Dedon PC, Begley TJ. (2022) Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2123529119. doi: 10.1073/pnas.2123529119. Epub 2022 Sep 12. PMCID: PMC9499598.

Finet O, Yague-Sanz C, Krüger LK, Tran P, Migeot V, Louski M, Nevers A, Rougemaille M, Sun J, Ernst FGM, Wacheul L, Wery M, Morillon A, Dedon P, Lafontaine DLJ, Hermand D. (2022) Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation. Mol Cell. 2022 Jan 20;82(2):404-419.e9. doi: 10.1016/j.molcel.2021.11.003. Epub 2021 Nov 18. PMCID: PMC8792297.

Kaiser S, Byrne SR, Ammann G, Asadi Atoi P, Borland K, Brecheisen R, DeMott MS, Gehrke T, Hagelskamp F, Heiss M, Yoluç Y, Liu L, Zhang Q, Dedon PC, Cao B, Kellner S. (2021) Strategies to Avoid Artifacts in Mass Spectrometry-Based Epitranscriptome Analyses. Angew Chem Int Ed Engl. 2021 Oct 25;60(44):23885-23893. doi: 10.1002/anie.202106215. Epub 2021 Sep 29. PMCID: PMC8597057.